Profile
Dr Ann CHOW
Principal Investigator
Dr Ann Chow has over 20 years of research experience in crystallization science, modelling and control, formulation science and technology. Upon graduation from Cambridge, she joined the Chemical and Processing Engineering Centre (CPEC) in NUS (the predecessor of Institute of Chemical and Engineering Sciences) as a research fellow to set up a crystallization research team. She is now the team leader for formulation science team. Her research interests include crystallization fundamentals, crystallization process development, control and monitoring of crystallization process using process analytical technology (PAT) tools, effect of impurities/additives on crystal habit and polymorph, cocrystal development, particle technology and formulation development. She has led multi-disciplinary research projects in numerous collaborations with industry (e.g. GSK, MSD, Syngenta, AstraZeneca, P&G, Nestle) and overseas universities, including University in Illinois at Urbana Champaign (UIUC), Imperial College London and University of Manchester. She has published more than 120 journal papers and 2 book chapters.
Dr Chow is a Principal Investigator on the PIPS project "Building a Capability in Magnetic Resonance Methods for the Pharmaceutical and Agrochemical Sector within PIPS".
Singapore
Researchers
PIPS
Research Interest
Key Publications
Google Scholar Link
Aitipamula, S.; Chow, P. S.; Tan, R. B. H. Trimorphs of a Pharmaceutical Cocrystal Involving Two Active Pharmaceutical Ingredients: Potential Relevance to Combination Drugs. CrystEngComm 2009, 11 (9), 1823–1827. https://doi.org/10.1039/B904616J.
Aitipamula, S.; Chow, P. S.; Tan, R. B. H. Polymorphism in Cocrystals: A Review and Assessment of Its Significance. CrystEngComm 2014, 16 (17), 3451. https://doi.org/10.1039/c3ce42008f.
Fujiwara, M.; Chow, P. S.; Ma, D. L.; Braatz, R. D. Paracetamol Crystallization Using Laser Backscattering and ATR-FTIR Spectroscopy: Metastability, Agglomeration, and Control. Crystal Growth & Design 2002, 2 (5), 363–370. https://doi.org/10.1021/cg0200098.