This page contains a list of CARES projects that have been completed:
Data2Knowledge in the Digital Manufacture of Pharmaceuticals
June 2020 – September 2022
This project was led by Professors Alexei Lapkin and Markus Kraft with funding from PIPS via A*STAR. One aspect of the digitalisation of chemical manufacturing focuses on creating a digital twin of the physical entities that bridges the gap between the cyber- and the real-world, shortening the time span from design to the delivery of the target product to the end-users. This project used technologies developed as part of The World Avatar (TWA) project. A semantically integrated system with agents operating on the knowledge graph was constructed and deployed for test runs in both Singapore and Cambridge laboratories, optimised in particular for the CARES laboratory. The results thus far have primarily explored the chemical space; nonetheless, the demonstration serves as a proof of concept for the dynamic knowledge graph-based approach to closed-loop optimisation. Read more about PIPS.
Development of Multi-Step Processes in Pharma
June 2019 – June 2022
The project was led by Professor Alexei Lapkin with funding from PIPS via A*STAR. For a given active pharmaceutical ingredient (API), the complexity of the multi-step chemical synthesis and purification, and the enormous number of possible reagent and reaction condition combinations are significant bottlenecks for rapid large-scale manufacturing. This project focuses on developing a novel automated self-optimising system that can rapidly identify sustainable and high-yielding multi-step chemistry and purification routes in tandem. This will be achieved by combining programmable chemical handling equipment, analytical tools and machine learning. This project has developed a new software package which is being transferred to the companies co-funding the PIPS programme. Read more PIPS.
Consumer Energy Usage Data in Smart City Development (CEUS)
October 2020 – March 2022
CEUS was a seed-funded Intra-CREATE collaborative project between Cambridge CARES and the Singa-pore-ETH Centre. The CEUS project complements Singapore’s pursuit of more decarbonised, resilient, and affordable electricity supply in the electricity market through its aims to lay the groundwork for Singapore consumers to manage their energy usage and cost. The objectives of CEUS were to develop new consumer semantics and innovative user interfaces, and explore options to integrate real-time energy consumption data that is sensitive to policy nuances within a smart city context. See more about CEUS
Cambridge Alternative Finance Collaboration Network (CAFCN)
January 2021 – March 2022
CAFCN was set up by the Cambridge Centre for Alternative Finance (CCAF), with the foundational support of the Foreign and Commonwealth Development Office. Through it’s research collaboration with Cambridge CARES alongside a bi-lateral programmatic relationship between the Asian Development Bank Institute and the CCAF, CAFCN aimed to accelerate tech-enabled financial innovation and knowledge sharing across the Asia-Pacific region. See more about CAFCN
eCO₂EP: A chemical energy storage technology
January 2018 – June 2021
eCO₂EP was a three-year programme, bringing together researchers from the University of Cambridge, the University of California, Berkeley, the National University of Singapore (NUS) and Nanyang Technological University (NTU) to develop ways of transforming carbon dioxide (CO₂) emitted as part of the industrial process into compounds that are useful in the chemical industry supply chain. Read about eCO₂EP and see the list of publications.
Rapid Industrialisation of Next Generation Nanomaterials (RINGs)
March 2019 – February 2021
The goal of the RINGs project (Rapid industrialization of next generation nanomaterials) was to develop and commercialise scalable processes for advanced nanomaterial synthesis. In this project, co-funded by the SMART Innovation Centre and led by Dr Nicholas JOSE (Research Fellow, CARES), continuous microreactors, machine learning and automated methods were combined as a platform for materials development and scale-up. The proof-of-concept project was the rapid development of antibacterial nano-ZnO coatings. Research from the RINGs project is now being further developed by the spin-off Accelerated Materials.