Profile

Dr Jun WU

Research Fellow

Research Interest

Interested in carbohydrate chemistry

- sugar editing
- photocatalysis
- electrocatalysis

Key Publications

1. Wu, J., Purushothaman, R., Kallert, F., Homölle, S. L., Ackermann, L. ''Electrochemical Glycosylation via Halogen-Atom-Transfer for C-Glycoside Assembly'' ACS Catal. 2024, 11532–11544.

2. Wu, J., Wei, W., Pohlmann, J., Purushothaman, R., Ackermann, L. ''Domino meta-C-H Ethyl Glycosylation by Ruthenium(II/III) Catalysis: Modular Assembly of meta-C-Alkyl Glycosides'' Angew. Chem. Int. Ed. 2023, 62, e202219319.

3. Wu, J., Kaplaneris, N., Pohlmann, J., Michiyuki, T., Yuan, B., Ackermann, L. ''Remote C-H Glycosylation by Ruthenium(II) Catalysis: Modular Assembly of meta-C-Aryl Glycosides'' Angew. Chem. Int. Ed. 2022, 61, e202208620.

4. Wu, J., Kopp, A., Ackermann, L. ''Synthesis of C-Oligosaccharides through Versatile C(sp(3) )-H Glycosylation of Glycosides'' Angew. Chem. Int. Ed. 2022, 61, e202114993.

5. Wang, W.[+], Wu, J.[+], Kuniyil, R., Kopp, A., Lima, R. N., Ackermann, L. ''Peptide Late-Stage Diversifications by Rhodium-Catalyzed Tryptophan C7 Amidation'' Chem 2020, 6, 3428–3439. (co-first author)

6. Wu, J., Kaplaneris, N., Ni, S., Kaltenhauser, F., Ackermann, L. ''Late-stage C(sp(2))-H and C(sp(3))-H glycosylation of C-aryl/alkyl glycopeptides: mechanistic insights and fluorescence labeling'' Chem. Sci. 2020, 11, 6521–6526.

7. Wu, J., Tang, Y., Wei, W., Wu, Y., Li, Y., Zhang, J., Zheng, Y., Xu, S. ''Phosphine-Catalyzed Activation of Vinylcyclopropanes: Rearrangement of Vinylcyclopropylketones to Cycloheptenones'' Angew. Chem. Int. Ed. 2018, 57, 6284–6288.

Achievements

remote C-H glycosylation for the target synthesis of C-alkyl/aryl glycosides, fluorescent glycopeptide, and oligosaccharide.