Profile

Prof Malini OLIVO

Collaborator

Malini Olivo is the Distinguished A*STAR Fellow and Distinguished Principal Scientist at the A*STAR Skin Research Labs (A*SRL), where she leads the Translational Biophotonics Laboratory. She is concurrently an Adjunct Professor at the Department of Obstetrics & Gynaecology, National University Health System (NUS), Singapore and the Royal College of Surgeons in Ireland. Widely regarded as a pioneer in clinical applications of optical diagnostics and therapeutics, she has made groundbreaking contributions to photomedicine and biophotonics. With over 30 years of experience, she has led advancements in biophotonics, analytical point-of-care technologies, and wearable devices, addressing critical needs in oncology, dermatology, cardiology, respiratory health, and women’s health. She has spearheaded five first-in-human clinical trials utilizing biophotonics innovations to improve healthcare outcomes, particularly in skin cancer, breast cancer, and inflammatory skin conditions such as eczema and psoriasis. Her research has bridged the gap between cutting-edge optical technologies and unmet clinical needs.

Prof. Malini has published over 500 scientific papers and holds more than 75 patents in medical technology platforms. She has secured over $50 million in competitive research funding globally, supporting innovations in photoacoustic hybrid imaging, confocal Raman spectroscopy, surface-enhanced Raman spectroscopy, and diffuse optics for clinical imaging and biosensing. She also co-founded two MedTech companies, further translating her research into impactful healthcare solutions. Her international prominence and scientific excellence have earned her prestigious accolades, including the SingHealth Research Excellence Award for cancer diagnostics and therapeutics. In 2024, she received the Singapore President’s Technology Award for her team's groundbreaking integration of biophotonics, machine learning, and clinical data in developing Respiree.

Prof. Malini is widely recognized as a leading woman in photonics, honored by SPIE, OPTICA, and AIMBE for her contributions. She has been elected as a Fellow of the Optical Society of America (OPTICA), the American Institute for Medical and Biological Engineering (AIMBE), the Institute of Physics, and the Singapore National Academy of Science (SNAS). She ranks among the top 2% of the world’s most cited scientists, according to Stanford University. Her advisory roles extend across numerous international boards, contributing to the advancement of photomedicine globally. She has also been a member of the Nobel subcommittee, further solidifying her impact on the field. Prof. Malini's work continues to influence the development of next-generation medical technologies, ensuring her legacy as a trailblazer in translational biophotonics.

Malini_Olivo@asrl.a-star.edu.sg

Singapore

Collaborators

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Research Interest

Key Publications

Google Scholar Link

Zhang, S., Liu, Y., Liao, W., Tan, R. R. Z., Bi, R., & Olivo, M. (2024). Ex Vivo Tissue Classification Using Broadband Hyperspectral Imaging Endoscopy and Artificial Intelligence: A Pilot Study. IEEE Sensors Journal. Published on 18 Jun 2024. (IF:4.3)

Sally Shuxian Koh*, Kapil Dev, Javier Jingheng Tan, Valerie Xinhui Teo, Shuyan Zhang, U. S Dinish *, Malini Olivo* and Daisuke Urano*, “Classification of plant endogenous states using machine learning-derived agricultural indices”, Plant Phenomics, vol. 5, p. 0060, Jan. 2023.(IF: 7.6)

Jayakumar Perumal, Pyng Lee*, Kapil Dev, Hann Qian Lim, U.S. Dinish, Malini Olivo*. “Machine Learning Assisted Real-time Label Free SERS Diagnoses of Malignant Pleural Effusion due to Lung cancer” Biosensors, DOI: 10.3390/bios12110940. Published on 28 Oct 2022. (IF: 4.9)

Kapil Dev, Chris Jun Hui Ho, Renzhe Bi, Yik Weng Yew, Dinish U S, Amalina Binte Ebrahim Attia, Mohesh Moothanchery, Steven Thng Tien Guan, Malini Olivo*. “Machine Learning Assisted Handheld Confocal Raman Micro-Spectroscopy for Identification of Clinically Relevant Atopic Eczema Biomarkers.” Sensors, DOI: 10.3390/s22134674 Published on 21 June 2022. (IF: 3.4)

Paper 5. 58. Weng-I Katherine Chio, Jia Liu, Tabitha Jones, Jayakumar Perumal, Dinish U. S, Ivan P. Parkin, Malini Olivo, Tung-Chun Lee, “SERS multiplexing of methylxanthine drug isomers via host-guest size matching and machine learning”, J. Materials Chemistry C 2021; 9(37). DOI: 10.1039/D1TC02004H. IF: 7.3.

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Achievements

- Singapore Presidents Technology Award 2024
- Singapore National Academy of Science (SNAS) Fellowship 2024
- A*STAR Distinguished Fellowship 2024
- Women in GovTech 2021, for contribution to advancing tech to transform the public sector 2021
- Science Foundation Ireland National Award “The art and science of Cancer”, 2011
- Honouring Women in Optics, International Society for Optics and Photonics SPIE 2011