Dr Deepika SHUKLA

Research Fellow

Dr Deepika Shukla earned her PhD in Electronics and Communication Engineering from IIITDM Jabalpur, India in 2017, with her thesis “Development of affine video stabilization techniques using integral projects under challenging scenic conditions”. After her PhD, she served as Research Scientist at the National Brain Research Centre, Manesar, India (2016-2020), where she worked on identifying novel brain metabolic and imaging biomarkers using MRI/MRS for Alzheimer’s and Parkinson’s diseases. Most recently, she served as a Magnetic Resonance Physicist at Imperial College London (2021-2022) and one of its research sites at Perinatal Trial Unit foundation in Bangalore, India (2020-2021). She worked on diffusion tensor imaging and magnetic resonance spectroscopy to identify diagnostic marker for HIE neonates undergoing cooling therapy after birth.

Dr Deepika Shukla joined CLIC in April 2023 as a Research Fellow in CLIC’s Neuroimaging workgroup with Prof Annabel Chen Shen-Hsing as her PI. She is currently tasked with quality checks and developing processing and analysis pipelines for magnetic resonance spectroscopy data.

Singapore - NTU



Research Interest

- MR imaging & spectroscopy data acquisition, analysis, system set-up and parameter optimization
- MR safety screening, Patient handling Alzheimer’s disease and Parkinson’s disease
- Human Brain, Phantom MR data preparation, acquisition, processing, and analysis (1.5 T and 3.0 T)
- In vivo Multi-nuclei (1H, 31P, 19F) MR spectroscopy both SVS, MRSI (3T Philips Achieva)
- Structural and diffusion magnetic resonance imaging acquisition, processing and analysis

Key Publications

Google Scholar Link

Deepika Shukla, Pravat K Mandal, Ritwick Mishra, Divya Dwivedi, Manjari Tripathi and Khushboo Punjabi, Vaishali, “Hippocampal Glutathione Depletion and pH Increment in Alzheimer\'s Disease: An in vivo MRS Study”, Journal of Alzheimer’s Disease, Oct 2021, doi: 10.3233/JAD-215032, IOS.

Prof Sudhin Thayyil, Stuti Pant, Paolo Montaldo, Deepika Shukla, et al ,“Hypothermia for moderate or severe neonatal encephalopathy in low-income and middle-income countries (HELIX): a randomised controlled trial in India, Sri Lanka, and Bangladesh”, Lancet Global Health, Vol 9, no.9, E1273-E1285, September, 2021, DOI:

Deepika Shukla, Pravat K. Mandal, Manjari Tripathi, Gayatri Vishwakarma, Ritwick Mishra, Kanika Sandal “Quantitation of in vivo brain glutathione conformers in cingulate cortex among age-matched control, MCI, and AD patients using MEGA- PRESS”, Human Brain Mapping, 2020 Jan; 41(1):194-217, doi: 10.1002/hbm.24799, Wiley.

Deepika Shukla, Pravat K Mandal, Lars Ersland, Eli Renatee Grüner, Manjari Tripathi, Partha Raghunathan, Ankita Sharma, G.R. Chaithya, Khushboo Punjabi, Christopher Splaine “A Multi-Center Study on Human Brain Glutathione Conformation using Magnetic Resonance Spectroscopy”, Journal of Alzheimer’s Disease, October, 2018, 66, 517–532,DOI 10.3233/JAD-180648, IOS .