Dr Zhen GUO

Senior Research Fellow

Dr Zhen Guo obtained his Bachelor and Master degrees in chemistry at Wuhan University, China, and his PhD degree in chemical engineering at Nanyang Technological University, Singapore. He has been working in industry and academia for eight years. Dr Guo was a trained chemical engineer in heterogeneous catalysis and is now interested in computer aided chemical processes design.

He co-founded the company Chemical Data Intelligence (CDI) in 2020 which takes advantages of Big Data in Chemistry and works to develop network analysis tools that can help users to identify more sustainable routes to target products. Dr Guo along with another CARES Research Fellow Dr Nicholas Jose started the CARES Commercialisation Talks in 2020 where speakers from tech start-ups and chemical companies are invited each month to talk about scientific tech commercialisation.

Singapore - CARES



Research Interest

- Data mining
- Machine learning
- Chemoinfomatics

Key Publications

Google Scholar Link

Discovering Circular Process Solutions through Automated Reaction Network Optimization, JM Weber, Z Guo, AA Lapkin, ACS Engineering Au, 2022,

Reaction impurity prediction using a data mining approach, A Arun, Z Guo, S Sung, A Lapkin, 2022

Integration of biowaste into chemical reaction networks, A Arun, J Weber, Z Guo, A Lapkin, 2021, submited on chemrxiv

Chemical data intelligence for sustainable chemistry, JM Weber, Z Guo, C Zhang, AM Schweidtmann, AA Lapkin, Chem. Soc. Rev., 2021, 50, 12013-12036

Weber, Jana M., Zhen Guo, Chonghuan Zhang, Artur M. Schweidtmann, and Alexei A. Lapkin. 2021. ‘Chemical Data Intelligence for Sustainable Chemistry’. Chemical Society Reviews, September, 10.1039.D1CS00477H.

Finding Optimal Reaction Routes in Chemical Reaction Networks, JM Weber, Z Guo, P Liò, AA Lapkin, 2020 Virtual AIChE Annual Meeting

Guo, Zhen, Ning Yan, and Alexei A. Lapkin. 2019. ‘Towards Circular Economy: Integration of Bio-Waste into Chemical Supply Chain’. Current Opinion in Chemical Engineering 26, 2019, (December): 148–56.

Wang, C., Yang, Q., Wang, J., Zhao, J., Wan, X., Guo, Z., and Yang, Y. 2019. 'Application of support vector machine on controlling the silanol groups of silica xerogel with the aid of segmented continuous flow reactor', Chemical Engineering Science 199, 485-95,

Guo, Z., Lim, K. H., Chen, M., Thio, B. J. R., and Loo, B. L. W., 2017, 'Predicting cetane numbers of hydrocarbons and oxygenates from highly accessible descriptors by using artificial neural networks', Fuel 207, 344-51,

Zhou, Chunmei, Zhen Guo, Yihu Dai, Xinli Jia, Hao Yu, and Yanhui Yang. 2016. ‘Promoting Role of Bismuth on Carbon Nanotube Supported Platinum Catalysts in Aqueous Phase Aerobic Oxidation of Benzyl Alcohol’. Applied Catalysis B: Environmental 181 (February): 118–26.